Predicting Safer Pesticides

University of the Philippines, Los Baños
and Grand Challenges Canada


Pesticides are used around the world to increase crop yield and avoid starvation and malnutrition. However, this has come at the expense of harmful impacts on human and environmental health. Pesticides cause an estimated 26 million poisoning cases and 220 thousand deaths annually. To make pesticides safer, we simulate millions of compounds and identify the ones that target pests without causing toxicity in humans or other friendly species. Our technology allows us to investigate larger numbers of compounds via computer simulation and move human and environmental testing earlier into compound discovery, thereby letting us find better and safer compounds faster and more cheaply. We are working with Dr Marlon Manalo at the University of the Philippines, Los Baños, the premier institute in the Philippines focusing on agriculture, to integrate our predictive models into the pesticide development process. This work is supported by Grand Challenges Canada.

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March 21, 2014